Published Nov 6, 2026 8:49 AM EST There’s a new kid on the block in the toothpaste aisle. Next to the usual fluoride formulas, another option has been appearing: hydroxyapatite toothpaste. Hydroxyapatite is the same mineral found in tooth enamel, and some claim using hydroxyapatite toothpaste can help plug tiny cracks in your teeth. Many brands are touting the new toothpaste as an effective alternative to fluoride.