New prevention tools offer hope, but reaching young people remains a challenge. Harare, Zimbabwe – When Shaun Moyo started nursing at Parirenyatwa Hospital in Harare in the late 1990s, the effects of the HIV epidemic were visible in the hospital wards and beyond them. Patients filled the wards, she recalls, while funerals had become a familiar part of everyday life. Nearly three decades later, the picture has changed. Antiretroviral treatment has transformed the lives of people living with HIV.